验证数据展示
产品信息
28307-1-PBS targets RBM48 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag27277 Product name: Recombinant human C7orf64 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 68-367 aa of BC104865 Sequence: LYGAIEQYNALDEYPAEDFTEVYLIKFMNLQSARTAKRKMDEQSFFGGLLHVCYAPEFETVEETRKKLQMRKAYVVKTTENKDHYVTKKKLVTEHKDTEDFRQDFHSEMSGFCKAALNTSAGNSNPYLPYSCELPLCYFSSKCMCSSGGPVDRAPDSSKDGRNHHKTMGHYNHNDSLRKTQINSLKNSVACPGAQKAITSSEAVDRFMPRTTQLQERKRRREDDRKLGTFLQTNPTGNEIMIGPLLPDISKVDMHDDSLNTTANLIRHKLKEVISSVPKPPEDKPEDVHTSHPLKQRRRI 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 7 open reading frame 64 |
| 别名 | C7orf64, UPF0712 protein C7orf64, RNA-binding protein 48, HSPC304 |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC104865 |
| 基因名称 | C7orf64 |
| Gene ID (NCBI) | 84060 |
| RRID | AB_3742291 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q5RL73 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RBM48 (RNA Binding Motif Protein 48) is a gene encoding an RNA-binding protein, belonging to the RNA-binding motif protein family, which plays an important role in the splicing process of U12-type introns. Deletion of RBM48 leads to an increase in the retention of U12-type introns, which affects cell differentiation and proliferation. And mutations in RBM48 are associated with a variety of diseases. For example, U12 intron splicing defects are associated with myelodysplastic syndromes (MDS) and may increase the risk of acute myeloid leukemia (AML). RBM48 may serve as a prognostic marker in certain cancers, such as renal smoky cell carcinoma, renal clear cell carcinoma, and hepatocellular carcinoma.
