验证数据展示
产品信息
20154-1-PBS targets RAD9B in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag14009 Product name: Recombinant human RAD9B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 83-426 aa of BC068031 Sequence: CKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVTLAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDLIEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVCCRKEFNGSDAKYFCII 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | RAD9 homolog B (S. pombe) |
| 别名 | hRAD9B, RAD9 homolog B (S. pombe) |
| 计算分子量 | 426 aa, 48 kDa |
| 观测分子量 | 48 kDa |
| GenBank蛋白编号 | BC068031 |
| 基因名称 | RAD9B |
| Gene ID (NCBI) | 144715 |
| RRID | AB_3741978 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6WBX8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RAD9B is a key member of the DNA damage response and cell cycle checkpoint family. Homologous to RAD9A, it typically functions as a subunit of the 9-1-1 complex (RAD9B-RAD1-HUS1), which is loaded onto chromatin in response to DNA damage or replication stress. This complex activates the ATM/ATR kinase pathway to mediate cell cycle arrest, DNA repair, or apoptosis.
