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RAC2 Polyclonal antibody

RAC2 Polyclonal Antibody for WB, IP, ELISA
Cat No. 20573-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, ELISA

Small G protein, Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inJurkat cells, HL-60 cells
Positive IP detected inMOLT-4 cells
Planning an IHC experiment? We recommend our IHCeasy RAC2 Ready-To-Use IHC Kit. RAC2 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

20573-1-AP targets RAC2 in WB, IP, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse
文献引用反应性mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
别名 Small G protein, Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022
计算分子量 21 kDa
观测分子量 21 kDa
GenBank蛋白编号NM_002872
基因名称 RAC2
Gene ID (NCBI) 5880
RRIDAB_10694419
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP15153
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome. The antibody is specific to RAC2.

实验方案

Product Specific Protocols
WB protocol for RAC2 antibody 20573-1-APDownload protocol
IP protocol for RAC2 antibody 20573-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Int J Mol Sci

NEDD4L Suppresses Proliferation and Promotes Apoptosis by Ubiquitinating RAC2 Expression and Acts as a Prognostic Biomarker in Clear Cell Renal Cell Carcinoma

Authors - Manlong Qi
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