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验证数据展示

  • WB analysis using 83740-4-RR (same clone as 83740-4-PBS)

    WB analysis using 83740-4-RR (same clone as 83740-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83740-4-RR (RAB37 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83740-4-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 83740-4-RR (same clone as 83740-4-PBS)

    IP experiment of mouse brain using 83740-4-RR (same clone as 83740-4-PBS)

    IP result of anti-RAB37 (IP:83740-4-RR, 4ug; Detection:83740-4-RR 1:2000) with mouse brain tissue lysate 1840 ug. This data was developed using the same antibody clone with 83740-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83740-4-RR

    Affinity and Kinetic Characterization of 83740-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83740-4-RR against Human RAB37 were performed. The affinity constant is 1.25 nM.

RAB37 Recombinant monoclonal antibody, PBS Only

RAB37 Uni-rAb® Recombinant Antibody for WB, IP, Indirect ELISA
Cat No. 83740-4-PBS

产品说明书

CloneNo. 240838D6

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IP, Indirect ELISA

别名

Ras-related protein Rab-37, Ras related protein Rab 37, 240838D6

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83740-4-PBS targets RAB37 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3717

Product name: Recombinant human RAB37 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-223 aa of BC016615

Sequence: MTGTPGAVATRDGEAPERSPPCSPSYDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMSSERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAGHQADEPSFQIRDYVESQKKRSSCCSFM

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 RAB37, member RAS oncogene family
别名 Ras-related protein Rab-37, Ras related protein Rab 37, 240838D6
计算分子量 223 aa, 25 kDa
观测分子量25 kDa
GenBank蛋白编号BC016615
基因名称 RAB37
Gene ID (NCBI) 326624
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ96AX2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAB37, as a small GTPase, plays important roles in several cellular processes through intracellular membrane traffic. RAB37 can regulate insulin secretion in β-cells 7 and TNF-α secretion from activated macrophages. In allergic responses, RAB37 regulated mast cell degranulation. RAB37 has been identified to be a tumor suppressor and it regulated exocytosis of several proteins including TIMP metallopeptidase inhibitor 1 (TIMP1), secreted frizzled-related protein-1 (SFRP1) 12, thrombospondin-1 (TSP1), and soluble ST2.

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