Na Pseudouridine Monoclonal antibody, PBS Only

Pseudouridine Monoclonal Antibody for Dot Blot, ELISA, Indirect ELISA
Cat No. 68578-1-PBS

产品说明书

CloneNo. 1G7C7

宿主/亚型

Mouse / IgG1

种属反应性

chemical compound

应用

Dot Blot, ELISA, Indirect ELISA

Ψ, 5-ribosyluracil

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

68578-1-PBS targets Pseudouridine in Dot Blot, ELISA, Indirect ELISA applications and shows reactivity with chemical compound samples.

经测试应用 Dot Blot, ELISA, Indirect ELISA Application Description
经测试反应性 chemical compound
免疫原 PTG 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 Pseudouridine
别名 Ψ, 5-ribosyluracil
基因名称
Gene ID (NCBI)
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Pseudouridine is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond. Pseudouridine is the most abundant RNA modification in cellular RNA (PMID: 29104216). After transcription and following synthesis, RNA can be modified with over 100 chemically distinct modifications. These can potentially regulate RNA expression post-transcriptionally, in addition to the four standard nucleotides and play a variety of roles in the cell including translation, localization and stabilization of RNA. Pseudouridine in rRNA and tRNA has been shown to fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation (PMID: 10902565, PMID: 23391857, PMID: 28045575). Pseudouridine in snRNA has been shown to enhance spliceosomal RNA-pre-mRNA interaction to facilitate splicing regulation (PMID 27268497).

Protocol for Dot Blot:
https://www.ptglab.com/protocol/68578-1-IgDotBlot.pdf

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