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验证数据展示

  • IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of mouse kidney using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of mouse liver using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    IHC staining of human colon cancer using 15152-1-AP (same clone as 15152-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15152-1-AP (Prokineticin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

  • IF Staining of NIH/3T3 using 15152-1-AP (same clone as 15152-1-PBS)

    IF Staining of NIH/3T3 using 15152-1-AP (same clone as 15152-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using Prokineticin 1 antibody (15152-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 15152-1-PBS in a different storage buffer formulation.

Prokineticin 1 Polyclonal antibody, PBS Only

Prokineticin 1 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 15152-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IF/ICC, Indirect ELISA

别名

PROK1, EG VEGF, EGVEGF, EG-VEGF, Endocrine-gland-derived vascular endothelial growth factor

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

15152-1-PBS targets Prokineticin 1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag5098

Product name: Recombinant human PROK1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-105 aa of BC025399

Sequence: MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKIPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 prokineticin 1
别名 PROK1, EG VEGF, EGVEGF, EG-VEGF, Endocrine-gland-derived vascular endothelial growth factor
计算分子量 12 kDa
GenBank蛋白编号BC025399
基因名称 Prokineticin 1
Gene ID (NCBI) 84432
RRIDAB_3669199
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP58294
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Prokineticin 1 (PROK1) is also named as EG-VEGF and Mambakine, belongs to the to the AVIT (prokineticin) family. Prokineticin signaling comprises two secreted proteins (Prok-1 and Prok-2) and two cognate G-protein coupled receptors (PK-R1 and PK-R2) that are widely expressed in different tissues and of great versatility. Prokineticins were shown to promote angiogenesis in steroidgenic glands, heart and reproductive organs (PMID:18440852). PROK1 has been described as a secretory protein with pleiotropic functions and as a novel tissue-specific angiogenic factor (PMID:32355954). EG-VEGF/PK-1, described as selective angiogenic mitogen, is widely expressed in different tissues including steroidogenic endocrine glands (PMID:16320832). A lot of data suggests EG-VEGF to be restricted to endocrine glands and to some endocrine-dependent organs (PMID:28386275).

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