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验证数据展示

  • WB analysis using 86669-1-RR

    WB analysis using 86669-1-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 86669-1-RR (Phospho-TAU (Thr205) antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • WB analysis using 86669-1-RR (same clone as 86669-1-PBS)

    WB analysis using 86669-1-RR (same clone as 86669-1-PBS)

    Phosphatase inhibitor treated and λ phosphatase treated mouse brain tissue were subjected to SDS PAGE followed by western blot with 86669-1-RR (Phospho-TAU (Thr205) antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with GAPDH antibody (60004-1-Ig) as loading control. This data was developed using the same antibody clone with 86669-1-PBS in a different storage buffer formulation.

Phospho-TAU (Thr205) Recombinant monoclonal antibody, PBS Only

Phospho-TAU (Thr205) Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 86669-1-PBS

产品说明书

CloneNo. 251173E12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

MAPT, TAU, AT180, DDPAC, MAPTL

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86669-1-PBS targets Phospho-TAU (Thr205) in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 microtubule-associated protein tau
别名 MAPT, TAU, AT180, DDPAC, MAPTL
计算分子量 37-46, 79-81 kDa
观测分子量45-60 kDa
GenBank蛋白编号BC000558
基因名称 TAU
Gene ID (NCBI) 4137
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP10636
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tau is hyperphosphorylated during aging and in age-related neurodegenerative diseases such as Alzheimer's disease (AD) and fronto-temporal dementia. Hyperphosphorylation of Tau leads to the formation of neurofibrillary tangles (NFT) in the neurons and glia cells, which is one of the hallmarks of AD.

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