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验证数据展示

  • WB analysis using 16575-1-AP

    WB analysis using 16575-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 16575-1-AP (PTOV1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PTOV1 Polyclonal antibody

PTOV1 Polyclonal Antibody for WB, ELISA
Cat No. 16575-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

别名

ACID2, Activator interaction domain-containing protein 2, PP642, prostate tumor overexpressed 1, Prostate tumor-overexpressed gene 1 protein

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inmouse testis tissue, rat testis tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

16575-1-AP targets PTOV1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag9859

Product name: Recombinant human PTOV1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 57-416 aa of BC042921

Sequence: MEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGMGG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 prostate tumor overexpressed 1
别名 ACID2, Activator interaction domain-containing protein 2, PP642, prostate tumor overexpressed 1, Prostate tumor-overexpressed gene 1 protein
计算分子量 416 aa, 47 kDa
观测分子量58 kDa
GenBank蛋白编号BC042921
基因名称 PTOV1
Gene ID (NCBI) 53635
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86YD1
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PTOV1 is a dual-domain adaptor and transcriptional co-regulator that promotes cell proliferation and oncogenic signaling through interactions with E2F1, RSK, and Mediator components. Shuttling between cytoplasm and nucleus, it integrates growth factor and differentiation pathways to balance proliferation and differentiation. Overexpressed in multiple cancers-most prominently prostate carcinoma-PTOV1 is linked to tumor progression, therapy resistance, and poor prognosis, positioning it as a potential biomarker and therapeutic target in epithelial malignancies. (PMID: 15713644)

实验方案

Product Specific Protocols
WB protocol for PTOV1 antibody 16575-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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