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验证数据展示

  • IHC staining of human lymphoma using 10480-1-AP

    IHC staining of human lymphoma using 10480-1-AP

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:100 (under 25x lens).

Prothymosin Alpha Polyclonal antibody

Prothymosin Alpha Polyclonal Antibody for IHC, ELISA
Cat No. 10480-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, ELISA

别名

Prothymosin alpha, prothymosin, alpha, PTMA, TMSA

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inhuman lymphoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10480-1-AP targets Prothymosin Alpha in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原 Prothymosin Alpha fusion protein Ag0732 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 prothymosin, alpha
别名 Prothymosin alpha, prothymosin, alpha, PTMA, TMSA
计算分子量 12 kDa
GenBank蛋白编号BC003510
基因名称 Prothymosin Alpha/PTMA
Gene ID (NCBI) 5757
RRIDAB_2174388
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP06454
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

实验方案

Product Specific Protocols
IHC protocol for Prothymosin Alpha antibody 10480-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols