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验证数据展示

  • WB analysis using 87958-1-RR (same clone as 87958-1-PBS)

    WB analysis using 87958-1-RR (same clone as 87958-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87958-1-RR (PSME2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87958-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 87958-1-RR (same clone as 87958-1-PBS)

    IHC staining of mouse liver using 87958-1-RR (same clone as 87958-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 87958-1-RR (PSME2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87958-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME2 antibody included
  • IHC staining of rat liver using 87958-1-RR (same clone as 87958-1-PBS)

    IHC staining of rat liver using 87958-1-RR (same clone as 87958-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 87958-1-RR (PSME2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87958-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PSME2 antibody included
  • Affinity of 87958-1-RR

    Affinity of 87958-1-RR

    Biolayer interferometry (BLI) kinetic assays of 87958-1-RR against Human PSME2 were performed. The affinity constant is 0.52 nM.

PSME2 Recombinant monoclonal antibody, PBS Only

PSME2 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 87958-1-PBS

产品说明书

CloneNo. 253556B5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

PA28B, PA28beta, REG beta, REGbeta, REG-beta

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy PSME2 Ready-To-Use IHC Kit. PSME2 primary antibody included.

产品信息

87958-1-PBS targets PSME2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3986

Product name: Recombinant human PSME2 protein

Source: e coli.-derived, T-HIS

Tag: 6*His

Domain: 1-239 aa of BC019885

Sequence: MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVPKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGEEKPSMY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
别名 PA28B, PA28beta, REG beta, REGbeta, REG-beta
计算分子量 239 aa, 27 kDa
观测分子量 27 kDa
GenBank蛋白编号BC019885
基因名称 PSME2
Gene ID (NCBI) 5721
RRIDAB_3745837
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9UL46
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The principal function of the proteasome is targeted degradation of intracellular proteins. Activity of the 20S proteasome is controlled by regulatory complexes that bind to the ends of the cylindrical proteasome. 11S regulator (REG or PA28), is a complex of 28 kDa subunits that is thought to activate proteasomes toward the production of antigenic peptides. Human PSME1 and PSME2 genes encode the two proteasome activators PA28 alpha and beta, respectively, which have been implicated in antigen processing for loading class I MHC molecules. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

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