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PSMC3IP Polyclonal antibody

PSMC3IP Polyclonal Antibody for WB, IHC, IF/ICC, IP, ELISA
Cat No. 11339-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, ELISA and More (1)

PSMC3-interacting protein, PSMC3 interacting protein, Proteasome 26S ATPase subunit 3-interacting protein, HOP2, Homologous-pairing protein 2 homolog

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHEK-293 cells, K-562 cells, Jurkat cells
Positive IP detected inJurkat cells
Positive IHC detected inmouse testis tissue, rat testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inHepG2 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:400-1:1600
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11339-1-AP targets PSMC3IP in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 PSMC3IP fusion protein Ag1883 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 PSMC3 interacting protein
别名 PSMC3-interacting protein, PSMC3 interacting protein, Proteasome 26S ATPase subunit 3-interacting protein, HOP2, Homologous-pairing protein 2 homolog
计算分子量 25 kDa
观测分子量 24-29 kDa
GenBank蛋白编号BC008792
基因名称 PSMC3IP
Gene ID (NCBI) 29893
RRIDAB_2172642
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9P2W1
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PSMC3IP, also called HOP2, encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis.

实验方案

Product Specific Protocols
WB protocol for PSMC3IP antibody 11339-1-APDownload protocol
IHC protocol for PSMC3IP antibody 11339-1-APDownload protocol
IF protocol for PSMC3IP antibody 11339-1-APDownload protocol
IP protocol for PSMC3IP antibody 11339-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell

Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis.

Authors - Nam Woo Cho
  • KD Validated
mouseIF

Nucleic Acids Res

RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis

Authors - Chao Liu
humanWB

Cell Rep

MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

Authors - Anabel Zelceski
human

Nat Commun

Promotion of homology-directed DNA repair by polyamines.

Authors - Chih-Ying Lee
humanWB,IF

Oncotarget

A study of meiomitosis and novel pathways of genomic instability in cutaneous T-cell lymphomas (CTCL).

Authors - Matthew Tsang
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