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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68534-1-Ig (same clone as 68534-1-PBS)

    WB analysis using 68534-1-Ig (same clone as 68534-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68534-1-Ig (PRMT5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68534-1-PBS in a different storage buffer formulation.

PRMT5 Monoclonal antibody, PBS Only

PRMT5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68534-1-PBS

产品说明书

CloneNo. 4A1B5

宿主/亚型

Mouse / IgG1

种属反应性

Human, rat

应用

WB, Indirect ELISA

别名

72 kDa ICln binding protein, HRMT1L5, IBP72, Jak binding protein 1, JBP1, PRMT5, SKB1, SKB1 homolog, SKB1Hs

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PRMT5 Ready-To-Use IHC Kit. PRMT5 primary antibody included.

产品信息

68534-1-PBS targets PRMT5 in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 PRMT5 fusion protein Ag9678 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 protein arginine methyltransferase 5
别名 72 kDa ICln binding protein, HRMT1L5, IBP72, Jak binding protein 1, JBP1, PRMT5, SKB1, SKB1 homolog, SKB1Hs
计算分子量 637 aa, 73 kDa
观测分子量 68 kDa
GenBank蛋白编号BC025979
基因名称 PRMT5
Gene ID (NCBI) 10419
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO14744
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5 is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for PRMT5 activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer.