验证数据展示
产品信息
25736-1-PBS targets PRIC285 in IP, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IP, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag22719 Product name: Recombinant human PRIC285 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1733-2080 aa of BC150283 Sequence: DTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | peroxisomal proliferator-activated receptor A interacting complex 285 |
| 别名 | 3'-5' exoribonuclease HELZ2, ATP-dependent RNA helicase PRIC285, EC:3.1.13.1, EC:3.6.4.13, Helicase with zinc finger 2, transcriptional coactivator |
| 计算分子量 | 2649 aa, 295 kDa |
| 观测分子量 | 294 kDa |
| GenBank蛋白编号 | BC150283 |
| 基因名称 | PRIC285 |
| Gene ID (NCBI) | 85441 |
| RRID | AB_3742156 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BYK8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PRIC285, also known as HELZ2, is a member of the E3 ubiquitin ligase family, specifically the RING finger protein family. Its principal function is to serve as a nuclear transcriptional co-regulator within the peroxisome proliferator-activated receptor (PPAR) signaling pathway, thereby influencing lipid metabolism and energy homeostasis through the regulation of gene expression.
