×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of Jurkat cells using 25590-1-AP (same clone as 25590-1-PBS)

    WB analysis of Jurkat cells using 25590-1-AP (same clone as 25590-1-PBS)

    WB result of PRDM15 (25590-1-AP, 1:500) with si-control and si-PRDM15 transfected Jurkat cells. This data was developed using the same antibody clone with 25590-1-PBS in a different storage buffer formulation.

  • WB analysis of MCF-7 using 25590-1-AP (same clone as 25590-1-PBS)

    WB analysis of MCF-7 using 25590-1-AP (same clone as 25590-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 25590-1-AP (PRDM15 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25590-1-PBS in a different storage buffer formulation.

  • IP experiment of MCF-7 using 25590-1-AP (same clone as 25590-1-PBS)

    IP experiment of MCF-7 using 25590-1-AP (same clone as 25590-1-PBS)

    IP result of anti-PRDM15 (IP:25590-1-AP, 5ug; Detection:25590-1-AP 1:500) with MCF-7 cells lysate 2500ug. This data was developed using the same antibody clone with 25590-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

PRDM15 Polyclonal antibody, PBS Only

PRDM15 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 25590-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IP, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

25590-1-PBS targets PRDM15 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag22296

Product name: Recombinant human PRDM15 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 791-1141 aa of BC067102

Sequence: KHCKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTAAATQFTNLQPVAVGHLTTPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLPPPQPQAPPQQAAQPQVQAEQQQQQMYSY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 PR domain containing 15
别名
计算分子量 1507 aa, 169 kDa
观测分子量 169 kDa
GenBank蛋白编号BC067102
基因名称 PRDM15
Gene ID (NCBI) 63977
RRIDAB_2880145
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP57071
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, called PR-plus and PR-minus, which differ by the presence or absence of the PR domain, respectively. The PR-plus product is underexpressed or disrupted in cancer cells, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining factor of malignancy. PRDM15 (PR domain-containing protein 15), also known as PFM15 or ZNF298, is a 1507 amino acid protein belonging to the PRDM family. Localizing to the nucleus, PRDM15 contains sixteen C2H2-type zinc fingers and one SET domain. It is believed to participate in transcriptional regulation and may be involved in cell differentiation and tumorigenesis. PRDM15 exists several isoform and molecular weight of respective isoform is 169 kDa, 135kda, 62kDa.

||
New chat

Able™

正在加载，请稍候...