验证数据展示
产品信息
13767-1-PBS targets PPM1H in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag4750 Product name: Recombinant human PPM1H protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-82 aa of BC040177 Sequence: MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | protein phosphatase 1H (PP2C domain containing) |
| 别名 | ARHCL1, EC:3.1.3.16, KIAA1157, Protein phosphatase 1H, URCC2 |
| 计算分子量 | 82 aa, 9 kDa |
| 观测分子量 | 50-56 kDa |
| GenBank蛋白编号 | BC040177 |
| 基因名称 | PPM1H |
| Gene ID (NCBI) | 57460 |
| RRID | AB_3741841 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9ULR3 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PPM1H (Protein phosphatase 1H ) is a member of a group of 3 PPM phosphatases that have been termed the 'PPM1H subfamily. In blood cells, PPM1H is expressed at high levels in basophils and lower levels in neutrophils and is very low or not detected in most other cells including monocytes. PPM1H is localized to the Golgi and its knockdown suppresses primary cilia formation, similar to pathogenic LRRK2 (PMID: 27599670, 31663853)
