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OCT2-Specific Polyclonal antibody

OCT2-Specific Polyclonal Antibody for WB, IHC, ELISA
Cat No. 18996-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

OCT2, OCT2-Specific, Octamer binding protein 2, OTF 2, OTF2, POU class 2 homeobox 2, POU2F2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse thymus tissue, human brain tissue, human spleen tissue, mouse kidney tissue, Raji cells
Positive IHC detected inhuman spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

18996-1-AP targets OCT2-Specific in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 POU class 2 homeobox 2
别名 OCT2, OCT2-Specific, Octamer binding protein 2, OTF 2, OTF2, POU class 2 homeobox 2, POU2F2
计算分子量 62 kDa
观测分子量52-66 kDa
GenBank蛋白编号NM_002698
基因名称 POU2F2
Gene ID (NCBI) 5452
RRIDAB_10596624
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP09086
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

OCT2, also named as POU2F2 and OTF2, belongs to the POU transcription factor family and Class-2 subfamily. OCT2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). OCT2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. It modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. The antibody is specific to OCT2. OCT2 can be detected 52-66 kDa (PMID: 15377492, PMID: 34010659).

实验方案

Product Specific Protocols
WB protocol for OCT2-Specific antibody 18996-1-APDownload protocol
IHC protocol for OCT2-Specific antibody 18996-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cancer Cell

Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

Authors - Chen Yang
humanWB

Mol Ther

miR-3687 Overexpression Promotes Bladder Cancer Cell Growth by Inhibiting the Negative Effect of FOXP1 on Cyclin E2 Transcription.

Authors - Qipeng Xie
human,mouseWB,IHC

Int J Oncol

Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis‑dependent AKT/mTOR signaling.

Authors - Lixiu Xu
humanWB

Biochem Biophys Res Commun

CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer.

Authors - Weigang Ren
  • KD Validated
WB

Toxicol In Vitro

Comparisons of segment-specific toxicity of platinum-based agents and cadmium using S1, S2, and S3 cells derived from mouse kidney proximal tubules.

Authors - Hitomi Fujishiro
mouseWB

Age (Dordr)

Aging increases the susceptibility of cisplatin-induced nephrotoxicity.

Authors - Jiagen Wen
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