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- KD/KO Validated
PINX1 Polyclonal antibody
PINX1 Polyclonal Antibody for IF/ICC, WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF/ICC, WB,ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | Jurkat cells, A431 cells, C6 cells, NIH/3T3 cells, HeLa cells |
Positive IF detected in | HeLa cells |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:2000-1:12000 |
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
KD/KO | See 3 publications below |
WB | See 6 publications below |
IHC | See 8 publications below |
产品信息
12368-1-AP targets PINX1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | IF/ICC, WB,ELISA |
Cited Applications | WB, IHC |
Tested Reactivity | human, mouse, rat |
Cited Reactivity | human |
Immunogen | PINX1 fusion protein Ag3043 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | PIN2-interacting protein 1 |
Synonyms | LPTL, LPTS, PIN2 interacting protein 1, Pin2 interacting protein X1, PINX1, Protein 67 11 3, TRF1 interacting protein 1 |
Calculated Molecular Weight | 328 aa, 37 kDa |
Observed Molecular Weight | 40 kDa |
GenBank Accession Number | BC015479 |
Gene Symbol | PINX1 |
Gene ID (NCBI) | 54984 |
RRID | AB_2164405 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q96BK5 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
实验方案
Product Specific Protocols | |
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WB protocol for PINX1 antibody 12368-1-AP | Download protocol |
IF protocol for PINX1 antibody 12368-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Oncogene Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.
| ||
Mol Cancer The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway. | ||
Am J Cancer Res PINX1 promotes malignant transformation of thyroid cancer through the activation of the AKT/MAPK/β-catenin signaling pathway.
| ||
Mol Cancer PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway. | ||
Cancer Sci Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma. |