验证数据展示
产品信息
85783-1-PBS targets PHLDA1 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | PHLDA1 fusion protein Ag13125 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | pleckstrin homology-like domain, family A, member 1 |
别名 | Apoptosis-associated nuclear protein, DT1P1B11, PHRIP, Pleckstrin homology-like domain family A member 1, PQ-rich protein |
计算分子量 | 45 kDa |
观测分子量 | 40 kDa |
GenBank蛋白编号 | BC018929 |
基因名称 | PHLDA1 |
Gene ID (NCBI) | 22822 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q8WV24 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PHLDA1, also known as PHRIP and TDAG51, is a multifunctional protein involved in various biological processes. It can induce apoptosis in various cell types, including T cells, hippocampal cells, endothelial cells, melanoma cells, and mouse embryonic fibroblasts(PMID: 30207029). PHLDA1 plays a role in inhibiting growth factor signaling and has been implicated in tumor suppression through its ability to repress Akt activity by binding to phosphatidylinositol (PIP) lipids(PMID: 36142223).