验证数据展示
产品信息
25188-1-PBS targets PFN3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag18131 Product name: Recombinant human PFN3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-137 aa of BC132952 Sequence: MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGILNKTVHELIRGLRMQGA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | profilin 3 |
| 别名 | Profilin-III, profilin-3 |
| 计算分子量 | 137 aa, 15 kDa |
| 观测分子量 | 14 kDa |
| GenBank蛋白编号 | BC132952 |
| 基因名称 | PFN3 |
| Gene ID (NCBI) | 345456 |
| RRID | AB_3742139 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P60673 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PFN3 also known as profilin-3, belongs to the profilin family, a family of actin-binding proteins that regulate the dynamics of actin in cells. PFN3 may be involved in spermatogenesis. (PMID: 11867228). Deletion or abnormal function of PFN3 may lead to male infertility, especially in disorders associated with abnormal sperm acrosome development (spherozoospermia)(PMID: 34869336).
