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验证数据展示

  • WB analysis of HeLa using 10946-1-AP (same clone as 10946-1-PBS)

    WB analysis of HeLa using 10946-1-AP (same clone as 10946-1-PBS)

    WB result of PEX3 antibody (10946-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-PEX3 transfected HeLa cells. This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 10946-1-AP (same clone as 10946-1-PBS)

    IF Staining of mouse brain using 10946-1-AP (same clone as 10946-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using PEX3 antibody (10946-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 10946-1-AP (same clone as 10946-1-PBS)

    IF Staining of mouse kidney using 10946-1-AP (same clone as 10946-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse kidney tissue using PEX3 antibody (10946-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10946-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

PEX3 Polyclonal antibody, PBS Only

PEX3 Polyclonal Antibody for WB, IF-P, ELISA
Cat No. 10946-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF-P, ELISA

别名

Peroxin 3, Peroxin-3, PEX

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存

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产品信息

10946-1-PBS targets PEX3 in WB, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-P, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag1384

Product name: Recombinant human PEX3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-228 aa of BC014551

Sequence: MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 peroxisomal biogenesis factor 3
别名 Peroxin 3, Peroxin-3, PEX
计算分子量 42 kDa
观测分子量 42 kDa
GenBank蛋白编号BC014551
基因名称 PEX3
Gene ID (NCBI) 8504
RRIDAB_2162392
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP56589
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that anchored in the peroxisomal membrane and essential for peroxisome biogenesis and integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.

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