验证数据展示
产品信息
CL488-80196 targets PEX14 (human specific) in applications and shows reactivity with Human samples.
经测试应用 | Application Description |
经测试反应性 | Human |
免疫原 | PEX14 (human specific) fusion protein Ag0932 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | peroxisomal biogenesis factor 14 |
别名 | Cell and organelle markers, dJ734G22.2, NAPP2, Peroxin 14, Peroxisome Marker, PEX14, PEX14 (human specific), Pex14p, PTS1 receptor docking protein |
计算分子量 | 41 kDa |
观测分子量 | 57 kDa |
GenBank蛋白编号 | BC006327 |
基因名称 | PEX14 |
Gene ID (NCBI) | 5195 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O75381 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PEX14 (peroxisomal biogenesis factor 14) is a peroxisomal membrane protein that is essential for protein docking onto the peroxisomes. It is a central component of the peroxisimal matrix protein import machinery and interacts with PEX5 and PEX19. PEX14 is ubiquitously expressed and defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK). This antibody can be used to detect endogenous PEX14 with an apparent molecular weight of 57 kDa (PMID: 16449325; 9653144) and recognize peroxisomal structures in human, monkey and mouse cells.
This antibody is specific to human PEX14. It can't detect mouse or rat PEX14.