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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse splenocytes using 98241-1-RR (same clone as 98241-1-PBS)

    FC experiment of mouse splenocytes using 98241-1-RR (same clone as 98241-1-PBS)

    1x10^6 untreated or GM-CSF treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone: 241728D8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD11c (N418) (APC-65130, Clone: N418). Cells were not fixed. This data was developed using the same antibody clone with 98241-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98241-1-RR (same clone as 98241-1-PBS)

    FC experiment of mouse splenocytes using 98241-1-RR (same clone as 98241-1-PBS)

    1x10^6 GM-CSF treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone:241728D8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody (98241-1-RR, Clone:241728D8) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98241-1-PBS in a different storage buffer formulation.

Anti-Mouse PD-L2/CD273 Rabbit Recombinant Antibody, PBS Only

PD-L2/CD273 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98241-1-PBS

产品说明书

CloneNo. 241728D8

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

CD273, Butyrophilin B7-DC, Btdc, B7-DC, B7dc

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98241-1-PBS targets PD-L2/CD273 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 programmed cell death 1 ligand 2
别名 CD273, Butyrophilin B7-DC, Btdc, B7-DC, B7dc
计算分子量28kDa
GenBank蛋白编号NM_021396.2
基因名称 Pdcd1lg2
Gene ID (NCBI) 58205
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9WUL5
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.