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验证数据展示

  • IP experiment of mouse skeletal muscle using 31966-1-AP

    IP experiment of mouse skeletal muscle using 31966-1-AP

    IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with mouse skeletal muscle tissue lysate 1040 ug.

  • IP experiment of rat skeletal muscle using 31966-1-AP

    IP experiment of rat skeletal muscle using 31966-1-AP

    IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with rat skeletal muscle tissue lysate 1800 ug.

PCDHB1 Polyclonal antibody

PCDHB1 Polyclonal Antibody for IP, ELISA
Cat No. 31966-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IP, ELISA

别名

Protocadherin beta-1, Protocadherin Beta 1 , PCDH-beta-1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive IP detected inmouse skeletal muscle tissue, rat skeletal muscle tissue

推荐稀释比

应用推荐稀释比
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31966-1-AP targets PCDHB1 in IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IP, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 PCDHB1 fusion protein Ag35435 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protocadherin beta 1
别名 Protocadherin beta-1, Protocadherin Beta 1 , PCDH-beta-1
观测分子量80 kDa
GenBank蛋白编号BC112096
基因名称 PCDHB1
Gene ID (NCBI) 29930
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9Y5F3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PCDHB1 (Protocadherin Beta 1) is a member of the protocadherin beta gene cluster, which belongs to the Cadherin superfamily and is expressed primarily in the nervous system. It encodes a cell adhesion protein containing six extracellular adhesion protein structural domains and a distinct cytoplasmic tail involved in the establishment and function of intercellular junctions. PCDHB1 plays an important role in neurodevelopment, and its aberrant expression has been associated with a variety of neurodevelopmental disorders, for example, PCDHB1 expression is upregulated in the brains of patients with Rett syndrome, which may be related to the neuropathological features of the disease. In addition, members of the PCDHB1 gene cluster are involved in neuronal self-recognition, avoidance, and connection establishment with other neurons.

实验方案

Product Specific Protocols
IP protocol for PCDHB1 antibody 31966-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols