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PAX4 Polyclonal antibody

PAX4 Polyclonal Antibody for IF/ICC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC,ELISA

Conjugate

Unconjugated

Cat No : 13018-2-AP

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Synonyms

KPD, MODY9, paired box 4, Paired box protein Pax 4, PAX4

验证数据展示

  • IF Staining of A549 using 13018-2-AP

    IF Staining of A549 using 13018-2-AP

    Immunofluorescent analysis of A549 cells, using PAX4 antibody 13018-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

产品信息

13018-2-AP targets PAX4 in IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC,ELISA
Tested Reactivity human, mouse, rat
Immunogen PAX4 fusion protein Ag4111 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name paired box 4
Synonyms KPD, MODY9, paired box 4, Paired box protein Pax 4, PAX4
Calculated Molecular Weight 343 aa, 37 kDa
GenBank Accession NumberBC074761
Gene Symbol PAX4
Gene ID (NCBI) 5078
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO43316
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PAX4, a paired-box transcription factor, is a key regulator of pancreatic islet cell growth and differentiation. Differentiation of endoderm-derived endocrine pancreas is mediated through PAX4 and PAX6. PAX4 may act as a PAX6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. PAX4 has the potential to function as a tumor suppressor in human melanoma.