PAM Polyclonal antibody
PAM Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
发表文章中的应用
| WB | See 1 publications below |
产品信息
15464-1-AP targets PAM in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA |
| Cited Applications | WB |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Immunogen | PAM fusion protein Ag7762 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | peptidylglycine alpha-amidating monooxygenase |
| Synonyms | PAL, PAM, Peptidylamidoglycolate lyase, PHM |
| Calculated Molecular Weight | 108 kDa |
| GenBank Accession Number | BC018127 |
| Gene Symbol | PAM |
| Gene ID (NCBI) | 5066 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P19021 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PAM(Peptidyl-glycine alpha-amidating monooxygenase) is a multifunctional protein containing 2 enzymes,PHM and PAL. The PAM protein containing the peptide encoded by exon A (Type B mRNA) is cleaved to form 41-and 43-kDa proteins,and the 75kDa PAM proteins is determined by lacking antigenic exon B(TypeA)(PMID:1740449).The substrate specificity of PAM is broad, and production of all a-amidated peptides may be dependent upon proteins encoded by the single copy PAM gene(PMID:8436961).It has 6 isoforms produced by alternative splicing.
发表文章
| Species | Application | Title |
|---|---|---|
J Biol Chem Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer. |