×
Use Able AI chat for product recommendations

验证数据展示

  • IHC staining of human breast cancer using 14340-1-AP (same clone as 14340-1-PBS)

    IHC staining of human breast cancer using 14340-1-AP (same clone as 14340-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 14340-1-AP (PALB2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14340-1-PBS in a different storage buffer formulation.

  • WB analysis using 14340-1-AP (same clone as 14340-1-PBS)

    WB analysis using 14340-1-AP (same clone as 14340-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14340-1-AP (PALB2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14340-1-PBS in a different storage buffer formulation.

PALB2 Polyclonal antibody, PBS Only

PALB2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14340-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

14340-1-PBS targets PALB2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag5654

Product name: Recombinant human PALB2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 841-1186 aa of BC044254

Sequence: TAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKALDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVLLKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQGMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAKESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIWDLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 partner and localizer of BRCA2
别名
计算分子量 131 kDa
观测分子量 130 kDa; 80-90 kDa; 250-260 kDa
GenBank蛋白编号BC044254
基因名称 PALB2
Gene ID (NCBI) 79728
RRIDAB_2158774
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86YC2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PALB2 can interact with BRCA1 and BRCA2 and form the BRCA1-PALB2-BRCA2 complex which is critical for homologous recombination and DNA damage response. PALB2 is an essential partner of BRCA2 that promotes the localization and stability of BRCA2. The predicted MW of PALB2 is approximately 130 kDa, while the truncated PALB2 protein arround 80-90 kDa can also be detected in SDS-PAGE similar to papers. (PubMed:16793542, 24141787, 24153426). There's the dimer form with MW 250-260 kDa (refer to PMID: 30289697).

||
New chat

Able™

正在加载，请稍候...