验证数据展示
产品信息
68042-1-PBS targets PAIP1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rabbit samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | Human, mouse, rabbit |
| 免疫原 |
CatNo: Ag16773 Product name: Recombinant human PAIP1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 102-400 aa of BC005295 Sequence: EQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSGNFRQLLLQRCRTEYEVKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNWGRVHATSTYREATPENDPNYFMNEPTFYTSDGVPFTAADPDYQEKYQELLEREDFFPDYEENGTDLSGAGDPYLDDIDDEMDPEIEEAYEKFCLESERKRKQ 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | poly(A) binding protein interacting protein 1 |
| 别名 | PABP interacting protein 1, PAIP 1, PAIP1 |
| 计算分子量 | 70 kDa |
| 观测分子量 | 40-45kDa, 62kDa |
| GenBank蛋白编号 | BC005295 |
| 基因名称 | PAIP1 |
| Gene ID (NCBI) | 10605 |
| RRID | AB_2918784 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9H074 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PAIP1 is a PABP-binding protein that contains two distinct PABP-binding motifs (PAMs). PAM1 binds to RNA recognition motif 2 in the N terminus of PABP; PAM2, which is a conserved region comprising approximately 15 amino acids, binds to the PABC domain of PABP. PAIP1 acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs.



