验证数据展示
产品信息
20354-1-PBS targets PA1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag14198 Product name: Recombinant human C16orf53 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-254 aa of BC003640 Sequence: MSLARGHGDTAASTAAPLSEEGEVTSGLQALAVEDTGGPSASAGKAEDEGEGGREETEREGSGGEEAQGEVPSAGGEEPAEEDSEDWCVPCSDEEVELPADGQPWMPPPSEIQRLYELLAAHGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPVTPKDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEDPSPASPPLRSSGSSLFPRQRKY 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 16 open reading frame 53 |
| 别名 | C16orf53, GAS, Glutamate-rich coactivator interacting with SRC1, PAGR1, PAXIP1 Associated Glutamate Rich Protein 1 |
| 计算分子量 | 254 aa, 28 kDa |
| 观测分子量 | 40-42 kDa |
| GenBank蛋白编号 | BC003640 |
| 基因名称 | PA1 |
| Gene ID (NCBI) | 79447 |
| RRID | AB_3741990 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BTK6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PAGR1 (PAXIP1 Associated Glutamate Rich Protein 1), also known as PA1 or C16orf53, the PA1 protein forms a complex with the histone H3K4 methyltransferases MLL3 and MLL4 and interacts with PAXIP1 (PAX Interacting Protein 1). PA1 is associated with the DNA damage response, is involved in early embryonic development, and may play a key role in male reproduction. PA1 has estrogen receptor binding activity and is involved in the endogenous positive regulation of the intracellular estrogen receptor signaling pathway.
