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验证数据展示

  • WB analysis using 86776-1-RR (same clone as 86776-1-PBS)

    WB analysis using 86776-1-RR (same clone as 86776-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86776-1-RR (CDH3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86776-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 86776-1-RR (same clone as 86776-1-PBS)

    IF Staining of A431 using 86776-1-RR (same clone as 86776-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using P-cadherin antibody (86776-1-RR, Clone: 251775F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86776-1-PBS in a different storage buffer formulation.

P-cadherin Recombinant monoclonal antibody, PBS Only

P-cadherin Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 86776-1-PBS

产品说明书

CloneNo. 251775F5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

Cadherin 3, Cadherin-3, CDH3, CDHP, HJMD

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86776-1-PBS targets P-cadherin in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Eg5236

Product name: Recombinant Human P-cadherin protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 108-440 aa of NM_001793.5

Sequence: DWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cadherin 3, type 1, P-cadherin (placental)
别名 Cadherin 3, Cadherin-3, CDH3, CDHP, HJMD
计算分子量91 kDa
观测分子量120 kDa
GenBank蛋白编号NM_001793.5
基因名称 P-cadherin
Gene ID (NCBI) 1001
RRIDAB_3745112
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP22223-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.

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