验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, mouse liver tissue, mouse ovary tissue, rat ovary tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
15248-1-AP targets OSGIN1 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC, IP |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag4295 Product name: Recombinant human OSGIN1 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 130-477 aa of BC032476 Sequence: AWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLTRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | oxidative stress induced growth inhibitor 1 |
| 别名 | BDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, huOKL38, OKL38 |
| 计算分子量 | 61 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC032476 |
| 基因名称 | OSGIN1 |
| Gene ID (NCBI) | 29948 |
| RRID | AB_2156401 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9UJX0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
OSGIN1, also named as BDGI and OKL38, belongs to the OKL38 family. OSGIN1 is a gene linked to oxidative stress and cell death in other tissues, was markedly upregulated in smokers compared to nonsmokers (PMID: 28548877). OSGIN1 has 3 isoforms with the molecular mass of 38, 52 and 61 kDa (PMID: 28181536).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for OSGIN1 antibody 15248-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Hazard Mater METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells. | ||
Cell Mol Life Sci OSGIN1 is a novel TUBB3 regulator that promotes tumor progression and gefitinib resistance in non-small cell lung cancer | ||
Toxicol Lett LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
| ||
J Pharmacol Exp Ther Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress. | ||
Toxicol Lett OSGIN1 regulates PM2.5-induced fibrosis via mediating autophagy in an in vitro model of COPD | ||
Int J Mol Sci Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2 |
