验证数据展示
产品信息
27598-1-PBS targets ORMDL3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag26253 Product name: Recombinant human ORMDL3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-100 aa of BC071833 Sequence: MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ORM1-like 3 (S. cerevisiae) |
| 别名 | ORM1 like protein 3 |
| 计算分子量 | 153 aa, 17 kDa |
| 观测分子量 | 17 kDa |
| GenBank蛋白编号 | BC071833 |
| 基因名称 | ORMDL3 |
| Gene ID (NCBI) | 94103 |
| RRID | AB_3742242 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8N138 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ORMDL3 (ORM1-like 3) is an endoplasmic-reticulum (ER)-resident transmembrane protein that negatively regulates serine palmitoyl-transferase (SPT), the first and rate-limiting enzyme of de-novo sphingolipid biosynthesis, thereby controlling cellular ceramide levels. (PMID: 31376405)
