NeutraControl HGF Monoclonal antibody, PBS Only

NeutraControl HGF Monoclonal Antibody for ELISA, Non-Neutralization
Cat No. 69527-1-PBS

产品说明书

CloneNo. 2G4G8

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

ELISA, Non-Neutralization

HGF, HGF Alpha, 2G4G8, Hepatocyte growth factor, Hepatocyte growth factor alpha chain

缓冲液配方:  PBS Only
Sterile PBS
PBS Only
偶联物:  Unconjugated
规格价格库存


69527-1-Ig

Planning an IHC experiment? We recommend our IHCeasy HGF Ready-To-Use IHC Kit. HGF primary antibody included.

产品信息

69527-1-PBS targets HGF in applications and shows reactivity with human samples.

经测试应用 ELISA, Non-Neutralization Application Description
经测试反应性 human
免疫原 human Humankine HGF protein HZ-1084 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 hepatocyte growth factor (hepapoietin A; scatter factor)
别名 HGF, HGF Alpha, 2G4G8, Hepatocyte growth factor, Hepatocyte growth factor alpha chain
基因名称 HGF
Gene ID (NCBI) 3082
偶联类型 Unconjugated
纯化方式Protein A purification
UNIPROT IDP14210
储存缓冲液 PBS Only, pH 7.4.
储存Store at -80°C.

背景介绍

Hepatocyte growth factor (HGF) is the most potent mitogen of mature hepatocytes in primary culture. HGF is derived from a biologically inactive single chain precursor of 728 amino acids (pro-HGF) localized mostly on the cell surface and in the extracellular matrix. The mature form produced following proteolytic cleavage is composed of a 69-kDa α-subunit (containing four kringle domains) and the 34 kDa β-subunit, similar to the catalytic domain of serine proteases, but with amino acid substitutions in the active site. HGF is a pleiotropic cytokine which exerts a variety of effects on several cells, being involved in the regulation of many biological processes, such as inflammation, tissue repair, morphogenesis, angiogenesis, tumour propagation, immunomodulation of viral infections and cardio-metabolic activities.

This antibody is a neutralizing control antibody for HGF, the immunogen is the same as Neutrakine 69027-1-Ig but could not neutralize human HGF.

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