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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85923-1-RR (same clone as 85923-1-PBS)

    WB analysis using 85923-1-RR (same clone as 85923-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85923-1-RR (SERPINI1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85923-1-PBS in a different storage buffer formulation.

  • WB analysis using 85923-1-RR (same clone as 85923-1-PBS)

    WB analysis using 85923-1-RR (same clone as 85923-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85923-1-RR (Neuroserpin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85923-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 85923-1-RR (same clone as 85923-1-PBS)

    IHC staining of mouse brain using 85923-1-RR (same clone as 85923-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85923-1-RR (Neuroserpin antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85923-1-PBS in a different storage buffer formulation.

Neuroserpin Recombinant antibody, PBS Only

Neuroserpin Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 85923-1-PBS

产品说明书

CloneNo. 250112E7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, pig

应用

WB, IHC, Indirect ELISA

别名

Serpin I1, Peptidase inhibitor 12, PI 12, PI12, PI-12

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85923-1-PBS targets Neuroserpin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, pig
免疫原 Neuroserpin fusion protein Eg2819 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 serpin peptidase inhibitor, clade I (neuroserpin), member 1
别名 Serpin I1, Peptidase inhibitor 12, PI 12, PI12, PI-12
计算分子量46 kDa
观测分子量 46 kDa
GenBank蛋白编号NM_005025.4
基因名称 Neuroserpin
Gene ID (NCBI) 5274
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99574
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuroserpin is a member of the serpin family of serine protease inhibitors predominantly expressed in the nervous system, such as s the cerebral cortex, hippocampus and the spinal cord.Neuroserpin exerts protective effects in neurons against excitotoxicity both in vitro and in vivo. Its proteolytic inhibitory activity is shown to protect neurons against damage caused by plasmin activation. Mice overexpressing neuroserpin exhibited loss of tPA activity in the brain. Overexpression of neuroserpin in primary neurons leads to increased dendritic arborization and altered dendritic spine shape.