验证数据展示
经过测试的应用
| Positive WB detected in | fetal human brain tissue, rat brain tissue, mouse brain tissue |
| Positive IHC detected in | human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | A549 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 4 publications below |
产品信息
11999-1-AP targets TrkC in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, IHC, IF/ICC, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | TrkC fusion protein Ag2635 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | neurotrophic tyrosine kinase, receptor, type 3 |
| 别名 | NTRK3, EC:2.7.10.1, GP145 TrkC, gp145(trkC), GP145-TrkC |
| 计算分子量 | 839 aa, 94 kDa |
| 观测分子量 | 94 kDa |
| GenBank蛋白编号 | BC013693 |
| 基因名称 | TrkC |
| Gene ID (NCBI) | 4916 |
| RRID | AB_2155428 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q16288 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TrkC (Tropomyosin Receptor Kinase C), also known as NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), belongs to the Trk family of receptor tyrosine kinases, which also includes TrkA and TrkB. These receptors are primarily involved in the development and function of the nervous system.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TrkC antibody 11999-1-AP | Download protocol |
| IHC protocol for TrkC antibody 11999-1-AP | Download protocol |
| IF protocol for TrkC antibody 11999-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Front Cell Dev Biol Identification of New miRNA-mRNA Networks in the Development of Non-syndromic Cleft Lip With or Without Cleft Palate. | ||
Stem Cell Res Ther NT3P75-2 gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model. | ||
iScience Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice. | ||
Transl Androl Urol Whole body vibration training promotes proprioceptive pathway for the treatment of stress urinary incontinence in rats |
