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验证数据展示

  • IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

    IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

    IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

NRG4 Polyclonal antibody, PBS Only

NRG4 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 27292-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

27292-1-PBS targets NRG4 in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag26044

Product name: Recombinant human NRG4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-62 aa of BC017568

Sequence: MPTDHEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSNLF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 neuregulin 4
别名
计算分子量 13 kDa
GenBank蛋白编号BC017568
基因名称 NRG4
Gene ID (NCBI) 145957
RRIDAB_3669591
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8WWG1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is expressed in multiple organs with the highest expression levels in brown adipose tissue. Neuregulin 4 is a secreted adipokine recently identified as playing an important role in modulating systemic energy metabolism and in the development of metabolic disorders in rodent and human obesity, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Nrg4 attenuates hepatic lipogenic signaling and preserves glucose and lipid homeostasis in obesity.

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