验证数据展示
产品信息
55113-1-PBS targets NPR2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) |
| 别名 | |
| 计算分子量 | 117 kDa |
| 观测分子量 | 111 kDa, 117 kDa |
| GenBank蛋白编号 | NM_003995 |
| 基因名称 | NPR2 |
| Gene ID (NCBI) | 4882 |
| RRID | AB_2881270 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P20594 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NPR2, also named as ANPRB, GC-B, NPR-B, ANPR-B and ANP-B, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the C-type natriuretic peptide NPPC/CNP hormone. NRP2 has guanylate cyclase activity upon binding of its ligand. It may play a role in the regulation of skeletal growth. NPR2 is the primary receptor for C type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Defects in NPR2 are the cause of acromesomelic dysplasia Maroteaux type (AMDM). The antibody is specific to NPR2.
