NOP2 Monoclonal antibody, PBS Only

NOP2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 68889-1-PBS

产品说明书

CloneNo. 1F4F4

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

Nucleolar protein 1, NSUN1, NOP120, NOL1, EC:2.1.1.-

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

68889-1-PBS targets NOP2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 NOP2 fusion protein Ag33985 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 NOP2 nucleolar protein homolog (yeast)
别名 Nucleolar protein 1, NSUN1, NOP120, NOL1, EC:2.1.1.-
计算分子量 120 kDa
观测分子量100-120 kDa
GenBank蛋白编号BC000656
基因名称 NOP2
Gene ID (NCBI) 4839
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP46087
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NOL1, (synonyms: p120, NSUN1, NOP120), is a 120 kDa proliferating-cell nucleolar antigen and is the most cancer specific of the proliferation-associated nucleolar proteins identified thus far. NOL1 is expressed in G1 and peaks during the early S phase of the cell cycle and it has not been detected in benign tumors and most normal resting tissues. Overexpression of NOL1 caused the transformation of NIH 3T3 cells and expression of an antisense NOL1 construct inhibited the growth of NIH 3T3 cells. NOL is localized in a novel nucleolar microfibrillar structure, and contains, consecutively, four major domains: a basic domain, an acidic domain, a hydrophobic and methionine-rich domain, and a domain rich in cysteine and proline residues. The gene for human NOL1 was assigned to chromosome 12p13 (PMID: 23775790).

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