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验证数据展示

  • WB analysis of THP-1 using 31067-1-AP (same clone as 31067-1-PBS)

    WB analysis of THP-1 using 31067-1-AP (same clone as 31067-1-PBS)

    IFN gamma treated THP-1 cells were subjected to SDS PAGE followed by western blot with 31067-1-AP (NLRC5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31067-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 31067-1-AP (same clone as 31067-1-PBS)

    IHC staining of human lung cancer using 31067-1-AP (same clone as 31067-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 31067-1-AP (NLRC5 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31067-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 31067-1-AP (same clone as 31067-1-PBS)

    IHC staining of human lung cancer using 31067-1-AP (same clone as 31067-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 31067-1-AP (NLRC5 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31067-1-PBS in a different storage buffer formulation.

NLRC5 Polyclonal antibody, PBS Only

NLRC5 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 31067-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Caterpiller protein 16.1, CLR16.1, NOD27, NOD4

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31067-1-PBS targets NLRC5 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag34508

Product name: Recombinant human NLRC5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-160 aa of BC063566

Sequence: MDPVGLQLGNKNLWSCLVRLLTKDPEWLNAKMKFFLPNTDLDSRNETLDPEQRVILQLNKLHVQGSDTWQSFIHCVCMQLEVPLDLEVLLLSTFGYDDGFTSQLGAEGKSQPESQLHHGLKRPHQSCGSSPRRKQCKKQQLELAKKYLQLLRTSAQQRYR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 NLR family, CARD domain containing 5
别名 Caterpiller protein 16.1, CLR16.1, NOD27, NOD4
计算分子量204 kDa
观测分子量200 kDa
GenBank蛋白编号BC063566
基因名称 NLRC5
Gene ID (NCBI) 84166
RRIDAB_3669840
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ86WI3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The nucleotide-binding domain leucine-rich repeat containing (NLR) family of proteins is mainly involved in microbial pathogen recognition, inflammatory responses, and cell death. NLRC5, the largest member of the NLR family, is currently receiving an increasing level of attention. NLRC5 plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.

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