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验证数据展示

  • WB analysis using 86920-2-RR (same clone as 86920-2-PBS)

    WB analysis using 86920-2-RR (same clone as 86920-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86920-2-RR (NGFR/TNFRSF16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86920-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86920-2-RR

    Affinity and Kinetic Characterization of 86920-2-RR

    Biolayer interferometry (BLl) kinetic assays of 86920-2-RR against Human NGFR/TNFRSF16 were performed. The affinity constant is 1.46 nM.

NGFR/TNFRSF16 Recombinant monoclonal antibody, PBS Only

NGFR/TNFRSF16 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 86920-2-PBS

产品说明书

CloneNo. 251010A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

NGFR, CD271, Gp80 LNGFR, Gp80-LNGFR, Low-affinity nerve growth factor receptor

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86920-2-PBS targets NGFR/TNFRSF16 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Eg4829

Product name: Recombinant Human NGFR/TNFRSF16 protein (rFc Tag)(HPLC verified)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 29-250 aa of NM_002507.4

Sequence: KEACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQPVVTRGTTDN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 nerve growth factor receptor (TNFR superfamily, member 16)
别名 NGFR, CD271, Gp80 LNGFR, Gp80-LNGFR, Low-affinity nerve growth factor receptor
计算分子量45 kDa
观测分子量70-75 kDa
GenBank蛋白编号NM_002507.4
基因名称 p75NTR
Gene ID (NCBI) 4804
RRIDAB_3745205
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP08138-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

p75NTR, also named TNFRSF16, Gp80-LNGFR, p75 ICD, and CD271, is a low-affinity receptor that can bind to NGF, BDNF, NT-3, and NT-4. It mediates cell survival as well as cell death of neural cells. The antibody is specific to NGFR.

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