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NFATC2IP Polyclonal antibody

NFATC2IP Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, WB,ELISA

Conjugate

Unconjugated

Cat No : 11667-1-AP

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Synonyms

NFATC2 interacting protein, NFATC2IP, NIP45

验证数据展示

  • WB analysis of mouse thymus using 11667-1-AP

    WB analysis of mouse thymus using 11667-1-AP

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11667-1-AP (NFATC2IP Antibody) at dilution of 1:100 incubated at 4 degree celsius over night.

  • IHC staining of human tonsillitis using 11667-1-AP

    IHC staining of human tonsillitis using 11667-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 11667-1-AP (NFATC2IP Antibody) at dilution of 1:50 (under 10x lens).

  • IHC staining of human tonsillitis using 11667-1-AP

    IHC staining of human tonsillitis using 11667-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 11667-1-AP (NFATC2IP Antibody) at dilution of 1:50 (under 40x lens).

产品信息

11667-1-AP targets NFATC2IP in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, WB,ELISA
Tested Reactivity human, mouse
Immunogen NFATC2IP fusion protein Ag2217 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
Synonyms NFATC2 interacting protein, NFATC2IP, NIP45
Calculated Molecular Weight 138 aa, 15 kDa
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC021551
Gene Symbol NFATC2IP
Gene ID (NCBI) 84901
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NCF5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NFATC2IP, also named as NIP45, is a 419 amino acid protein, which contains one ubiquitin-like domain. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. NFATC2IP In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.