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验证数据展示

  • WB analysis using 32043-1-AP

    WB analysis using 32043-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 32043-1-AP (NDFIP2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

NDFIP2 Polyclonal antibody

NDFIP2 Polyclonal Antibody for WB, ELISA
Cat No. 32043-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

Putative MAPK-activating protein PM04/PM05/PM06/PM07, NEDD4 WW domain-binding protein 5A, NEDD4 family-interacting protein 2, Nedd4 Family Interacting Protein 2, N4WBP5A

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inA431 cells, K-562 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

32043-1-AP targets NDFIP2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 NDFIP2 fusion protein Ag36480 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Nedd4 family interacting protein 2
别名 Putative MAPK-activating protein PM04/PM05/PM06/PM07, NEDD4 WW domain-binding protein 5A, NEDD4 family-interacting protein 2, Nedd4 Family Interacting Protein 2, N4WBP5A
计算分子量36kDa，336aa
观测分子量39 kDa
GenBank蛋白编号NM_019080.2
基因名称 NDFIP2
Gene ID (NCBI) 54602
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9NV92
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NDFIP2 (Nedd4 family interacting protein 2) is a gene encoding a membrane-anchored adapter protein involved in a variety of cellular processes. It regulates protein ubiquitination and degradation by binding to the Nedd4 family of E3 ubiquitin ligases.NDFIP2 has a wide intracellular distribution, including the Golgi, mitochondria, and perinuclear region of the cytoplasm. Its function involves negative regulation of gene expression, negative regulation of protein transport, and positive regulation of protein ubiquitination. In addition, NDFIP2 is associated with a variety of diseases, such as supratentorial ventricular meningiomas in children. In the cardiovascular field, NDFIP2 affects cardiac electrophysiologic function by regulating the degradation of hERG potassium channels. It is also involved in the immune response, affecting T cell function by regulating cytokine signaling pathways. In oncology, NDFIP2 has been found to affect the antiviral response by targeting IFITM3.

实验方案

Product Specific Protocols
WB protocol for NDFIP2 antibody 32043-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols