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NCOR2 Polyclonal antibody, PBS Only

NCOR2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 29952-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy NCOR2 Ready-To-Use IHC Kit. NCOR2 primary antibody included.

产品信息

29952-1-PBS targets NCOR2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag30727

Product name: Recombinant human NCOR2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1165-1363 aa of NM_006312

Sequence: SGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 nuclear receptor co-repressor 2
别名
计算分子量 274 kDa
观测分子量274 kDa
GenBank蛋白编号NM_006312
基因名称 NCOR2
Gene ID (NCBI) 9612
RRIDAB_3086197
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y618
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NCOR2, nuclear receptor corepressor 2 , is a transcriptional corepressor that that contains several nuclear receptor-interacting domains. NCOR2/SMRT acts as a platform protein, facilitating the recruitment of histone deacetylases to the DNA promoters bound by its interacting transcription factors (PMID: 9150137). NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription (PMID: 23081895).

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