Recombinant Mouse PON2 protein (rFc Tag)
种属
Mouse
纯度
>80 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >80 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse PON2 protein Ala30-Leu354 (Accession# Q62086) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 330260 |
| 蛋白编号 | Q62086 |
| 预测分子量 | 62.1 kDa |
| SDS-PAGE | 58-75 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
PON2 (Serum paraoxonase/arylesterase 2) has antioxidant activity and can prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. Highest levels of PON2 protein are found in the mouse lung and small intestine, followed by the heart and liver, while lower levels are present in the testis, kidney and brain.
参考文献:
1. Giordano, Gennaro et al. Toxicology and applied pharmacology vol. 256,3 (2011): 369-78. 2. Costa, Lucio G et al. Neurotoxicology vol. 43 (2014): 3-9. 3. Aviram, Michael, and Mira Rosenblat. Free radical biology & medicine vol. 37,9 (2004): 1304-16.
