Recombinant Mouse Mbl2 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3157

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Synonyms

Mannan-binding protein, Mannose-binding protein C, Mbl2, MBP-C, RA-reactive factor P28A subunit



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Mouse Mbl2 protein Glu19-Asp244 (Accession# P41317) with a rabbit IgG Fc tag at the C-terminus.
基因ID 17195
蛋白编号 P41317
预测分子量 50.0 kDa
SDS-PAGE 48-60 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Mbl2 (mannose-binding lectin 2), a member of the multimeric lectin family, is crucial in immune regulation and tumor development. Mbl2 serves as a crucial regulator of the innate immune response and represents a prime candidate for genetic association studies in cancer due to its genomic heterogeneity. Mbl2 activates a complement through the lectin pathway, recognizing and removing pathogens, such as microorganisms and viruses, apoptotic cells, and necrotic cells.

参考文献:

1. Maury C. P., et al. (2007). J Intern Med. Oct;262(4):466-9. 2. Baccarelli A, et al. (2006). Int J Cancer. Oct 15;119(8):1970-5. 3. Liao H, et al. (2023). Cancers. Oct 9;15(19):4900.