Recombinant Mouse Mbl2 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 |
Not tested |
来源 | HEK293-derived Mouse Mbl2 protein Glu19-Asp244 (Accession# P41317) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 17195 |
蛋白编号 | P41317 |
预测分子量 | 50.0 kDa |
SDS-PAGE | 48-60 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Mbl2 (mannose-binding lectin 2), a member of the multimeric lectin family, is crucial in immune regulation and tumor development. Mbl2 serves as a crucial regulator of the innate immune response and represents a prime candidate for genetic association studies in cancer due to its genomic heterogeneity. Mbl2 activates a complement through the lectin pathway, recognizing and removing pathogens, such as microorganisms and viruses, apoptotic cells, and necrotic cells.
参考文献:
1. Maury C. P., et al. (2007). J Intern Med. Oct;262(4):466-9. 2. Baccarelli A, et al. (2006). Int J Cancer. Oct 15;119(8):1970-5. 3. Liao H, et al. (2023). Cancers. Oct 9;15(19):4900.