Recombinant Mouse Haptoglobin protein (His Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse Haptoglobin protein Val19-Asn347 (Accession# Q61646) with a His tag at the C-terminus. |
| 基因ID | 15439 |
| 蛋白编号 | Q61646 |
| 预测分子量 | 37.9 kDa |
| SDS-PAGE | 45-55 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Haptoglobin(HP), also named as zonulin, is a plasma glycoprotein and belongs to the peptidase S1 family. As a kind of acute-phase response protein, serum Hp is mainly synthesized by hepatocytes and is widely distributed in the circulation in humans. The main physiological function of serum Hp is binding free hemoglobin released from red blood cell lysis and protecting tissues and vessels from oxidative damage. The level of Hp is a useful biomarker for some diseases diagnosis, such as Hepatocellular carcinoma, Pancreatic cancer, Type 2 diabetes mellitus, Diabetes kidney disease, and so on.
参考文献:
1. Andersen C B, et al. (2017). Antioxidants & Redox Signaling. 26(14):814. 2. Alayash A I, et al. (2013).Trends in Biotechnolog. 31(1):2-3. 3. Wang S, et al. (2019). Cardiovascular Diabetolog. 18(1). 4. Moriwaki K, et al. (2006). Japan Journal of Molecular Tumor Marker Research. 21(11):2803-2808. 5. Dalal K, et al. (2019). Clinica Chimica Acta. 495:309-317. 6. Shinton N K, et al. (1965). Journal of Clinical Pathology. 18(1):114-118. 7. Bhensdadia N M, et al. (2013). Kidney International. 83(6):1136-1143. 8. Gurung R L, et al. (2018). Scientific Reports. 8(1):5109.
