Recombinant Mouse CD9 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1397

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Synonyms

CD9 antigen, MIC3, P24, Tspan 29, TSPAN29



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Mouse CD9 protein Thr110-Ile193 (Accession# P40240) with a rabbit IgG Fc tag at the C-terminus.
基因ID 12527
蛋白编号 P40240
预测分子量 36.0 kDa
SDS-PAGE 35-45 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

The cell-surface molecule CD9, a member of the transmembrane-4 superfamily, interacts with the integrin family and other membrane proteins, and is postulated to participate in cell migration and adhesion. Expression of CD9 enhances membrane fusion between muscle cells and promotes viral infection in some cells. It is often used as a mesenchymal stem cell marker. The CD9 antigen appears to be a 227-amino acid molecule with four hydrophobic domains and one N-glycosylation site. As an organizer of multi-molecular membrane complexes, the tetraspanin CD9 has been implicated in a number of biological processes, including cancer metastasis, and is a candidate therapeutic target.

参考文献:

1. Tachibana I. et al. (1999). J Cell Biol. 146(4):893-904. 2. Meng X. et al. (2007). J Transl Med. 5:57. 3. Boucheix C. et al. (1991). J Biol Chem. 266(1):117-22. 4. SuwatthanarakT. et al. (2023). Biomater Adv. 146:213283