Recombinant Mouse CD21 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CD21 protein Ile12-Trp963 (Accession# P19070) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 12902 |
| 蛋白编号 | P19070 |
| 预测分子量 | 130.9 kDa |
| SDS-PAGE | 130-200 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Complement receptor type 2 (CR2, CD21) is a 145-kD glycosylated single polypeptide chain consisting of a long extracellular domain ofshort consensus repeat sequences, a transmembrane region and a short cytoplasmic domain. The receptor is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells. CD21 binds complement fragments C3d, C3dg and iC3b that are covalently bound to target antigens. On B cells, CD21 forms a complex together with CD19 and CD81 (TAPA-1), which functions as a co-receptor to the BCR.
参考文献:
1.Thorarinsdottir, K et al.Scandinavian journal of immunology vol. 82,3 (2015): 254-61. 2.Roozendaal, Ramon, and Michael C Carroll.Immunological reviews vol. 219 (2007): 157-66. 3.Wilbrink, Rick et al.Frontiers in immunology vol. 12 686273. 8 Jun. 2021.
