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Recombinant Mouse Beta-2-Microglobulin protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3086

Print datasheet

Synonyms

B2m, beta 2 microglobulin

验证数据展示

  • Purity of Recombinant Mouse Beta-2-Microglobulin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse Beta-2-Microglobulin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse Beta-2-Microglobulin protein Ile21-Met119 (Accession# P01887) with a rabbit IgG Fc tag at the C-terminus.
基因ID 12010
蛋白编号 P01887
预测分子量 37.7 kDa
SDS-PAGE 37-42 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.

参考文献:

1. Gao Y, Hong Y, et al. (2023) Cell. 186(5):1026-1038.e20. 
2. Enzan N, Matsushima S, et al. (2023) Circ Res. 132(9):1110-1126. 
3. Jheng JR, DesJardin JT, et al. (2024) scler Thromb Vasc Biol. 44(7):1570-1583. 
4. Zhao Y, Zheng Q, et al.  (2023) Nat Neurosci. 26(7):1170-1184.