验证数据展示
68525-1-Ig
产品信息
68525-1-PBS targets MYST2 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | Human, mouse, rat |
免疫原 | MYST2 fusion protein Ag5166 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | MYST histone acetyltransferase 2 |
别名 | HBO1, HBOA, KAT7, MYST 2, MYST2 |
计算分子量 | 611 aa, 71 kDa |
观测分子量 | 83 kDa |
GenBank蛋白编号 | BC032640 |
基因名称 | MYST2 |
Gene ID (NCBI) | 11143 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | O95251 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.