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验证数据展示

  • WB analysis using 14524-1-AP (same clone as 14524-1-PBS)

    WB analysis using 14524-1-AP (same clone as 14524-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14524-1-AP (MYBBP1A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14524-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 14524-1-AP (same clone as 14524-1-PBS)

    IHC staining of human kidney using 14524-1-AP (same clone as 14524-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 14524-1-AP (MYBBP1A antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14524-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MYBBP1A antibody included
  • IF Staining of HepG2 using 14524-1-AP (same clone as 14524-1-PBS)

    IF Staining of HepG2 using 14524-1-AP (same clone as 14524-1-PBS)

    Immunofluorescent analysis of HepG2 cells, using MYBBP1A antibody 14524-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye). This data was developed using the same antibody clone with 14524-1-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 14524-1-AP (same clone as 14524-1-PBS)

    IP experiment of HEK-293 using 14524-1-AP (same clone as 14524-1-PBS)

    IP result of anti-MYBBP1A (IP:14524-1-AP, 4ug; Detection:14524-1-AP 1:500) with HEK-293 cells lysate 2800ug. This data was developed using the same antibody clone with 14524-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 14524-1-AP (same clone as 14524-1-PBS)

    WB analysis of HEK-293 using 14524-1-AP (same clone as 14524-1-PBS)

    WB result of MYBBP1A antibody (14524-1-AP; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-MYBBP1A transfected HEK-293 cells. This data was developed using the same antibody clone with 14524-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

MYBBP1A Polyclonal antibody, PBS Only

MYBBP1A Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 14524-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

Myb binding protein 1A, Myb-binding protein 1A, PAP2

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy MYBBP1A Ready-To-Use IHC Kit. MYBBP1A primary antibody included.

产品信息

14524-1-PBS targets MYBBP1A in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag6008

Product name: Recombinant human MYBBP1A protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 979-1328 aa of BC050546

Sequence: STALSSFLTKRNSPLTVPMFLSLFSRHPVLCQSLLPILVQHITGPVRPRRQACLLLQKTLSMREVRSCFEDPEWKQLMGQVLAKVTENLRVLGEAQTKAQHQQALSSLELLNVLFRTCKHEKLTLDLTVLLGVLQGQQQSLQQGAHSTGSSRLHDLYWQAMKTLGVQRPKLEKKDAKEIPSATQSPISKKRKKKGFLPETKKRKKRKSEDGTPAEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTPAKSPKLQKKNQKPSQVNGAPGSPTEPAGQKQHQKALPKKGVLGKSPLSALARKKARLSLVIRSPSLLQSGAKKKAQVRKAGKP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 MYB binding protein (P160) 1a
别名 Myb binding protein 1A, Myb-binding protein 1A, PAP2
计算分子量 149 kDa
观测分子量 150-160 kDa
GenBank蛋白编号BC050546
基因名称 MYBBP1A
Gene ID (NCBI) 10514
RRIDAB_2148137
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BQG0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The protooncogene MYB is predominantly expressed in immature hemopoietic cells where it has an essential role in hemopoietic cell proliferation and differentiation. Oncogenically activated forms of MYB is generally N- and/or C-terminal truncations of the normal MYB protein. Removal of the C terminus of MYB disrupts or deletes a region termed the negative regulatory domain (NRD), resulting in an increase in DNA binding, transactivation, and transformation by MYB. One feature of the NRD is a leucine zipper-like motif [PMID: 8302594]. Murine Myb-binding protein-1a (MYBBP1A), originally called P160, was identified by its ability to interact specifically with Myb via this leucine zipper-like motif. MYBBP1A modulates MYB activity upon binding to the MYB NRD [PMID: 10644447, 9447996].

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